When refreshing a space I think walls should be uncomplicated neutral colours. There are many different shades of white and soft greys that give a sense of space and calm and are a great canvas to hang a favourite piece of art or print.
Neutral colours will allow interesting features in the house to stand out ie wood work, exposed stone, and brick work.
I like to choose internal colours by drawing on inspiration from treasured Pieces of art, precious possessions or by looking at the immediate landscape.
Personally I like to run a colour theme through the house, using soft furnishings, pottery, glass, art and lamp shades.
Never be worried about using bold splashes of colours together to create fun, warmth and interest.